Streptozotocin (STZ) selectively targets and destroys pancreatic beta cells by entering through GLUT2 transporters, causing DNA damage, oxidative stress, and ultimately cell death (necrosis/apoptosis), leading to severe insulin deficiency and diabetes
It could also alleviate the size of myocardial infarction and the subsequent decrease in cardiac function in rats [145]
[DOI] [PMC free article] [PubMed] [Google Scholar] 78.OShea TM, Allred EN, Dammann O, et al
TIGAR plays neuroprotective roles in MPP+/MPTP-induced Parkinsons disease by alleviating ferroptosis
Experimental Effects of Shulikang capsule on prevention of acute high altitude reaction
Jet Lag and Shift Work When your internal clock is out of sync with the real world, DSIP can help reset it