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In aged Rhesus monkeys, Epitalon treatment stimulated melatonin production and restored youthful secretion patterns, while also normalizing cortisol rhythms in a time-of-daydependent manner [59]

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Animal doses cannot be directly extrapolated to humans Key Research Findings# Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice , published in Biochemical Pharmacology (Neelakantan H et al., 2018

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