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In this regard, good results have been reached through photodynamic therapy, which is based on the generation of ROS after stimulation of a photosensitizer by light: cancer cells under treatment internalize porphyrin precursor molecules to induce the formation of ROS that lead to photooxidative stress and cancer-specific cell death 164,165

Moreover, the levels of the sphingolipid metabolite, sphingosine 1-phosphate, showed an obvious negative correlation with the concentrations of TNF- (r = -0.4495

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Gut microbiota in colorectal cancer: from pathogenesis to clinic