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P53 activates the downstream Bcl family of pro-apoptotic proteins (Bax, Bak, Bim, etc.) and reduces the number of anti-apoptotic proteins (Bcl-xl, Bcl-2, etc.), which triggers the release of Cyt-c from the mitochondria, and ultimately activates the downstream cytosolic asparagine caspases that cause apoptosis (Cederroth et al., 2024)

Yes, L-theanine can be taken either with meals or on an empty stomach

Lipid-based NPs Lipid-based NPs are known to be stable and possess less toxicity for in vivo applications

A Frizzled-like cysteine-rich domain in Glypican-3 mediates Wnt binding and regulates hepatocellular carcinoma tumor growth in mice