s-acetyl glutathione synergy Designs for Health S-Acetyl Glutathione Synergy - 60

doi: 10.1038/s41551-019-0406-3 44 PoliniAProdanovLBhiseNSManoharanVDokmeciMRKhademhosseiniA

Transfected cells were used for experiments, 3648 h (plasmids) or 72 h (siRNA) after transfection

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The reduced PPIXpeptide (compound 1 ) and oxidized version with both Met residues oxidized to MetO (compound 2 ) were synthesized by using standard, microwave-assisted Fmoc solid-phase peptide synthesis, followed by an on-resin coupling of PPIX and purification through high-performance liquid chromatography (HPLC) after cleavage (Supplementary Figs