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Ideally, ECTRs in VPA intoxications should be investigated in a controlled clinical trial setting, but this is difficult to plan/perform since the overall occurrence of VPA intoxications per center will be limited to few cases

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In T2D, dysbiosis is also associated with the development of insulin resistance

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Emerging evidence links folate pathway variants and folate receptor autoantibodies to autism spectrum disorder (ASD)

Conclusions: FE-PSLD is an efficacious strategy with favorable outcomes for managing LSS, shown by a significant reduction of pain level with a relatively short follow-up time after the procedure