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G/D-CuP was engineered to exert therapeutic effects across all phases of wound repair while targeting diverse pathological mechanisms, hence in vitro effects were validated
Over 29 days of treatment, the peptide inhibited pulmonary artery muscularization (the thickening and stiffening of pulmonary arteries that drives this condition), prevented right heart hypertrophy (the enlargement of the right ventricle that occurs when it has to pump against increased resistance), and significantly decreased mortality
Its emollient properties are beneficial in repairing the skin's barrier function
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The 0.4% retinol trial by Kafi et al
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