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[69] demonstrated that the knockdown of FoxO3a enhanced cellular senescence in human dermal fibroblasts indicating that FoxO3a might maintain cellular homeostasis, probably by enhancing autophagy

Finally, this growth advantage translated to faster growth of GGT1 + cells in vivo (Fig

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Also, the discovery of possible therapeutic strategies for the treatment of COVID-19 and PD is aided by the targeted suppression of caspases and nuclear factor kappa B activation [54]