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KPVs strongest preclinical evidence is for oral delivery to gut tissue, where inflamed intestinal cells actively absorb it via the PepT1 transporter (upregulated during inflammation)

Preliminary research also shows that pairing vitamin B12 supplementation with antidepressants could help significantly reduce symptoms of major depressive disorder to a greater extent than treatment with an antidepressant alone

All discussions of synergy are currently based on theoretical models and preclinical data for each compound individually

10.1016/j.jgr.2014.12.001 4 BaiY

AIT involves regular exposure to increasing doses of the allergenin this case, shellfish proteinsto induce desensitization and tolerance

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