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A five-parameter empirical model for correlating the solubility of solid compounds in supercritical carbon dioxide

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Jaszberenyi M, Rick FG, Szalontay L, Block NL, Zarandi M, Cai RZ, et al

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The authors reported that intra-articular AOD-9604 injection in the rabbit osteoarthritis model produced macroscopic, histologic, and biomechanical evidence of cartilage preservation relative to untreated controls, with the combination of AOD-9604 plus hyaluronic acid yielding the most consistent chondroprotective effect [4]