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10.3390/nu6020466 14 GalliF.BonominiM.BartoliniD.ZatiniL.ReboldiG.MarcantoniniG.et al (2022)

This combination downregulates Nrf2 in the cytoplasm while upregulating its nuclear expression, enhancing nuclear translocation and increasing HO-1 mRNA and protein expression

These signs go beyond normal pharmacological reactions and could indicate a complication

The polar methanolic extract of Hypericum perforatum is a prime candidate for future investigations because of its better performance towards physical and fluorescence activities, which could lead to its potential applicability to skin cancer via PDT [315]

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