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The cost reflects the specialized handling requirements and individualized dosing protocols necessary for optimal therapeutic outcomes

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2007, American College of Obstetricians & Gynecologists (US), 3 Wang Y, Sharma RK, Falcone T, Goldberg J, Agarwal A: Importance of reactive oxygen species in the peritoneal fluid of women with endometriosis or idiopathic infertility

NMDAR have been found in ECs forming the BBB

This discovery suggests that in the future, immune-suppressive agents may be used together with ADI-PEG20 for drug resistance due to ADI-PEG20 neutralizing antibodies upon prolonged treatment