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However, there are examples of altered -GCS activity associated with a variety of diseases

Identically to FK-506, it forms a complex with the cytosolic protein FKBP

Interestingly, BSO alone was insufficient to induce ferroptosis in MDA-MB-231 cells (Supplementary Fig

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The compound functions as a synthetic D-retro-inverso peptide carrying a shortened version of the FOXO4 segment that binds to p53, acting as a competitive inhibitor of this critical protein-protein interaction

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