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Ferritin and iron can promote the development of NAFLD through oxidative stress [24]

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worsening the deficiency in SAM synthetase

The interplay between mental health disorders and chronic health conditions complicates medical management, resulting in diminished treatment compliance and poorer health outcomes ( Several mechanisms have been proposed to underlie depression and anxiety, including alterations in monoaminergic and glutamatergic neurotransmission, deficits in neuroplasticity, hypothalamic-pituitary-adrenal (HPA) axis dysregulation, and elevated levels of neuroinflammation and oxidative stress (Wiebenga et al., 2022)