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Single-Dose Only No Preservatives: Sterile Water for Injection contains no preservatives, so each container is meant for a single use

Clin Transl Med

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Generalized Anaphylactic shock and death have been reported with administration of parenteral vitamin B12 (see WARNINGS)

Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease

Loading phase (deficiency): 1000 mcg IM or subQ daily or every other day for 1 to 2 weeks Maintenance: 1000 mcg monthly is a standard maintenance dose for conditions like pernicious anemia Wellness protocols: may use lower doses weekly, though this is less established clinically In ml: cyanocobalamin is typically supplied at 1000 mcg/ml, so a 1000 mcg dose equals 1 ml