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Recent studies indicate that accumulation of cadmium in the blood mediates progression of CKD and places smokers at higher risk for all-cause mortality

In fact, CDC data show that using tobacco products has become the leading contributor to preventable disease and death in the U.S., accounting for more than 480,000 deaths per year

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Additionally, current dual users had a significantly higher risk of CVD compared to current e-cigarette users, former cigarette users, and former e-cigarette users, with adjusted ORs of 1.28 (1.031.59), 1.30 (1.041.61), and 1.89 (1.232.90), respectively, although this risk did not significantly differ for comparisons with current cigarette and former dual users

But the interesting thing is that smoking filtered cigarettes could actually be worse than smoking unfiltered

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