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Movement patterns still need correction

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Bipolar disorder is also characterized by mutations to mtDNA and mitochondrial dysfunction caused predominantly by excess ROS (Andreazza et al

Collectively, this study identifies GGCT as a metabolic switch that diverts Gln flux toward GSH synthesis to maintain redox homeostasis, while enhancing glucose-fueled anaplerosis into the TCA cycle to sustain cell proliferation

Hence the observed increase in GSH activity (total and reduced glutathione) in the magnesium treated diabetic animals may possibly be due to its effect on the enzymes gamma glutamyl transpeptidase (GGT), glutamate cysteine ligase and glutathione synthetase respectively