N.KingS
Air pollutants have a negative impact on skin microflora (specific studies proved a decrease in residual skin microflora of about 50% in the presence of ozone) : these alterations can cause colonization of the stratum corneum with pathogenic strains of bacteria
Practical implication: higher doses do not proportionally extend effect duration because the rate-limiting step shifts from peptidase activity to tissue uptake capacity
Vitamin D receptors are expressed throughout the brain, and deficiency is associated with accelerated cognitive decline

Abbreviations ADI-R: Autism diagnostic interview - revised ALAD: Delta aminolevulinic acid dehydratase CARS: Childhood Autism Rating Scale CNS: Central nervous system d.f.: Degrees freedom DSM: American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders fGSH: Free reduced glutathione GCL: Glutamate cysteine ligase GCT: -glutamyl cyclotransferase GGT: -glutamyl-transferase GPx: Glutathione peroxidase GSH: Reduced glutathione GSH: GSSG: Glutathione redox ratio GSH-R: Glutathione reductase GS: Glutathione synthetase GSSG: Oxidised glutathione GST: Glutathione-S-transferases Mg 2+ : Magnesium ions Mn 2+ : Manganese ions Q: Cochran's Q (a measure of statistical heterogeneity) SMD: Standardised mean difference tGSH: Total glutathione References Wing L, Gould J: Severe impairments of social interaction and associated abnormalities in children: epidemiology and classification

Part of: Taraka SKK, Pasala PK, Sahoo RK, Laddha UD, Khairnar SJ, Bendale AR, Rudrapal M (2022) Atorvastatin ascorbic acid cocrystal strategy to improve the safety and efficacy of atorvastatin