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Several studies indicated that the inhibition of AR causes the accumulation of toxic aldehydes, such as 4-HNE [35-37], the most abundant lipid peroxidation products, also one of the substrates of AR [38]

Besides, the ENS exerts an indirect effect on skeletal health via the GM (212)

Tr li: Hiu qu ca Glutathione 600 c th gim i nu bn ngng s dng, c bit nu khng duy tr ch chm sc da v li sng lnh mnh

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In vivo , apigenin reduces the secretion of pro-inflammatory factors (IL-1, IL-6, and TNF-), reduces the expression of the DCs costimulatory molecules CXCR4 and MHCII, and reduces the number of Langerhans cells

Supported by metabolic research but not yet by controlled trials specific to GLP-1 medications