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The TIR domain of SARM1 has inherent NADase activity, which can cleave NAD + into nicotinamide, cADPR and ADPR

However, it should be used as part of a broader treatment plan, including therapies like PRP or stem cell treatments, to address the underlying causes of the condition

For longer-term storage, refrigerate at 2-8C

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This finding is particularly relevant because it demonstrates actual structural nerve improvement in a metabolic neuropathy model, not just a traumatic injury model

This means when you thaw it, the solution may no longer be a homogenous 0.9% concentration