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In general, tryptophan metabolism is also impaired in IBD
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These microbial metabolites could potentially affect Pnp, Xdh, Gsr, Idh1, Gpx7, and influence purine metabolism and glutathione metabolism
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These observations underline the potency of NFT as a pharmacological Nrf2 activator
The administration of hemin results in the boost of HO-1 expression and mitigates inflammatory responses in retinal ganglion cell injury in diabetic retinopathy, as well as diabetic wound healing, diabetic kidney function and [54,55,56]
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