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Aggregation changes the apparent molecular weight and can reduce bioactivity

[21] Se ha propuesto que el sistema redox glutatin, del cual la glutatin reductasa forma parte, es responsable casi por completo de la proteccin de los cristalinos contra el perxido de hidrgeno, porque estas clulas son deficientes en catalasa, una enzima que cataliza la descomposicin del perxido de hidrgeno

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Additionally, a condition known as rhabdomyolysis is also associated with several types of substance use, including cocaine, heroin, ketamine, methadone, and methamphetamine