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Under FFA stimulation or an HFD-induced microenvironment of fatty liver disease, activated KCs release more TNF- and IFN- (128)

Resources: Duzel, A., Vlainic, J., & Seiwerth, S

1-Page Summary Additional Materials Counterarguments Supplements and hormones may not be effective or safe for everyone, and their long-term effects are not fully understood

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There is a consensus that in diseases and following trauma these values may be 2 or 3 times higher [45]

In vitro and ex vivo evidence (animal models and T2D patients) supports the role of the AGE-RAGE pathway in promoting OxS-driven beta-cell dysfunction and decreased insulin secretion [106,107]