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Highlights Glutathione (GSH) is the most abundant endogenous antioxidant in brain Oxidative stress is a prominent feature of Alzheimer disease and MCI brain Elevation of GSH in vivo protects brain against AD-relevant Abeta(142) Elevation of GSH in brain induces several protective pathways Acknowledgements This work was supported in part by NIH grants to D.A.B

Occupational environment and exposure in underdeveloped countries lead to several skin diseases like wart, mycosis, dermatitis, skin ulcer, acne, hives, scabies, atopic dermatitis, skin infections, skin allergy and sometimes skin cancers [5,6]

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