This treatment strategy is based on limited data from studies that reported a modest survival advantage with neoadjuvant chemoradiotherapy when results from neoadjuvant chemoradiotherapy and subsequent surgery were compared with results from surgery alone
the inflation volume (mm, means SD) was assessed before and after application of spasmogens (histamine, serotonin, acetylcholine, bradykinine, i.v.) or NaBPC157 (10 minutes before repeated spasmogen application, i.v.)
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