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Improved Long-term Outcome With Chemoradiotherapy Strategies in Locoregionally Advanced Esophageal Cancer

5.1 Vitamin A In a randomized, controlled, phase 3 trial, arsenic acid, and all-trans retinoic acid (45 mg/m 2 ) treatment was applied in 235 patients with acute promyelocytic leukemia (140)

Common side effects include: Nausea and vomiting Diarrhoea or constipation Reduced appetite (which is also a therapeutic effect) Injection site reactions (redness, bruising, or mild discomfort) These effects are typically mild to moderate and tend to resolve as the body adjusts to the medication

10.1038/s41574-023-00874-9 30 CuiY.ZhangN

Puig M, Shubow S (2025) Immunogenicity of therapeutic peptide products: bridging the gaps regarding the role of product-related risk factors

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