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Overall, injecting CD5/ LNP-FAPCAR 2.2 significantly reduced the number of FAP-positive cells and rescued pulmonary fibrosis while treatment with PFD provided limited relief from fibrosis, which was possibly due to the short duration of the medication

doi: 10.1371/journal.pone.0183208 192

Symptoms develop gradually and may include: Hematological: Megaloblastic anemia, fatigue, weakness, pallor, shortness of breath, dizziness