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Together these studies provide compelling evidence for sulforaphanethrough NRF2-mediated cytoprotective pathwaysto reduce oxidative stress, neural inflammation and cell death in chemically-induced models of PD

10.1093/toxres/tfaa009 3 Abd RaniN

Astaxanthin attenuates cognitive deficits in Alzheimers disease models by reducing oxidative stress via the SIRT1/PGC-1 signaling pathway

Our signaling-defective mutant integrin inhibits the activation of the cytoplasmic tyrosine kinases FAK and Src, as well as the extracellular signal-regulated kinase, ERK [17, 24]

Our findings suggest that the novel hub gene GPX3 is involved in the neutrophil-driven oxidative stress-mediated pathogenesis of RA