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In March 2011, The Tobacco Products Scientific Advisory Committee (TPSAC) published a review of menthol cigarettes effect on youth and other vulnerable populations, a requirement of the Tobacco Control Act

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[71] Heating these flavorings releases toxic chemicals [72] and carcinogens such as carbon monoxide (CO), polycyclic aromatic hydrocarbons (PAHs), furans, phenols, aldehydes (such as acrolein), and acids, in addition to nitrogenous carcinogens, alcohols, and heavy metals, all of which are dangerous to human health

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Under favorable condition lesions may coalesce to become bigger lesions resulting in drying of leaves