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They are not permanent and need maintenance to sustain

It has been suggested that the exchange of copper between a variety of target-specific cytosolic chaperones and their targets in distinct compartments is driven by an increase in the copper binding affinity [148]

Journal of Clinical and Experimental Ophthalmology, S4(006)

The original rationale for studying the gastric pentadecapeptide was cytoprotection of gastrointestinal mucosa

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