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Ferritinophagy and ferroptosis in cerebral ischemia reperfusion injury

This phenotype was explored in both mouse models and in vitro with an anti-IL-23 antibody to block IL-23 signaling where mice experienced prolonged survival and decreased tumor burden, and CD8 + cells in mice and in vitro showed enhanced cytotoxicity in the IL-23-depleted state [154] (Fig

doi: 10.1016/j.jpsychores.2015.08.008 18 JasonLABentonMCValentineLJohnsonATorres-HardingS

The safety profile appears favorable for extended use based on available data, though long-term studies specifically on oral formulations do not exist

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