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Bile acid-induced toxicity in HepaRG cells recapitulates the response in primary human hepatocytes

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Iron is considerably more toxic to cells expressing CYP2E1 than to cells not expressing this enzyme, and it is suspected that low concentrations of iron may act as a protective factor for CYP2E1 -induced injury

Oral doses of 1000 g deliver 5 to 40 g, even if taken with food

Vitamin B12 promotes brain health through its role in the production of neurotransmitters (specific chemicals in our nervous system) and myelin, the protective membrane around nerves