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Centromeric inactivation during aging can lead to chromosome segregation defects, genomic instability and decreased cell proliferation, which has become an important driver of aging

described a patient with a novel BCS1L mutation who had slower disease progression, presenting with myopathy, focal motor seizures, and optic nerve atrophy (88)

Vitamin d3 protects against prednisolone-induced liver injury associated with the impairment of hepatic nf-b/inos/nitric oxide pathway

Under various conditions, p53 can induce or suppress ferroptosis through transcriptional regulation or PTMs (Pietsch et al., 2008

To assess if gut selenoprotein deficiency was mirrored in circulating cells, blood monocyte-derived macrophages were examined

P., Paulus G