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The QC for each 384-well plate consisted of coefficient of variation calculations for isotopically labeled internal standards added to each individual sample at the first sample preparation step to monitor matrix effects, utilizing identical aliquots of commercial pooled plasma for wells A1, D12 and H12 of each 96-well experimental plasma plate and preparing those identically to experimental samples (internal bracket QC sample), utilizing identical aliquots of commercial pooled plasma prepared external to the 96-well plate by hand (external bracket QC sample), and a preparation blank injected prior to each 384-well plate to assess background

Archived from the original on 27 September 2007

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03 The Protocol Five phases

154 Increase in expression of MAO-B is arguably linked to an aberrant activity of the urea cycle linked -amyloid