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The recycling of NADPH associates the GSH system to the pentose-phosphate pathway [66]

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Dynamic contrast-enhanced MRI, positron emission tomography tracers of hypoxia or fibroblast activity, and immune profiling of tumor biopsies can help identify patients with vascular, stromal or immune features that match a given TME modulation strategy [86,87,88]

However, unlike most types of arthritis, fibromyalgia does more than affect one or two joints