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doi: 10.1038/s41440-018-0144-z 114 PechenyakB

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Monitor renal function regularly and adjust the dosage as necessary

GSK3B is known for its role as a negative regulator for transcription factors, microtubules, and Wnt signalling, as well as in the hormonal control of glucose homeostasis as well as neurological disorders 26,27 This crystal structure reveals that VAL 135 and ASP 133 are important, and interactions with these amino acids may enhance the inhibitors activity (Fig

It functions in conjunction with GPX4 and GSH to inhibit lipid ROS and ferroptosis (60, 61)