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These harmful constituents in tobacco smoke can cause squamous metaplasia in which normal columnar olfactory epithelium is replaced by squamous epithelium

Stanton Glantz, a UC San Francisco professor who studies tobacco policies

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The problem is especially worrisome at the governmental level, where grants are awarded to earnest but inexperienced individuals for ambitious-sounding pilot projects on smoking cessation or prevention, with little likelihood that they can or will be replicated

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The fact that the author challenges the status quo by his unconventional representation of his main character, Holden, who just like him rejects the system in general adds the shocking factor to others