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In one sentence, the mechanism is receptor-mediated: GHRP binding to GHS-R1a activates a Gq/11-coupled phospholipase C cascade that mobilises intracellular calcium and triggers exocytosis of stored GH from the anterior pituitary, independent of hypothalamic GHRH signalling

doi: 10.1007/s13300-020-00931-w 156

Curcumin protects human chondrocytes from IL-l1 -induced inhibition of collagen type II and 1-integrin expression and activation of caspase-3: an immunomorphological study

Nawroth R, Poell G, Ranft A, Kloep S, Samulowitz U, Fachinger G, Golding M, Shima DT, Deutsch U, Vestweber D (2002) VE-PTP and VE-cadherin ectodomains interact to facilitate regulation of phosphorylation and cell contacts

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L-carnitine is often touted for its potential benefits in enhancing exercise performance and weight management