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TAR DNA-binding protein 43 (TDP-43) and FUS (fused in sarcoma) Research has identified the cellular protein TDP-43 as an important factor in the cause of ALS, especially the sporadic forms (Mackenzie 2007)

Monitoring these biomarkers helps detect diseases, track health, and guide treatment 45

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Moreover, internal triggers like excess sugar, processed foods, trans fats, and hormonal dysregulation (like insulin resistance or PCOS) can worsen acne and delay wound healing

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