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Proper injection technique and site rotation help minimize these local effects

The high dose compensates for potentially impaired absorption and ensures adequate tissue stores

The natural instinct is to aim the stream of water at the lyophilized cake sitting at the bottom of the vial

Draw the intended dose, then check for air bubbles and push any out

however, it did report a significant clinical response in 30% of children on B12, which correlated with significant improvements in GSH redox status following B12 injections

This is a meaningful finding given how often steroid injections precede the chronic tendon injuries patients bring to us