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Prepared for the 3rd International Conference on Smokeless Tobacco

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Additionally, hypoxia-inducible factor 1-alpha (HIF-1)-mediated hypoxia induced upregulation of BNIP3 and NIX/BNIP3L, which activated cell death pathways in solid tumors (Sowter et al., 2001)

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The actual number is skewed by very high prices in a handful of countries like Australia and New Zealand and very low prices in parts of Africa and Asia