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No high-quality clinical trial has demonstrated that B12 injections produce meaningful weight loss outcomes independent of dietary and exercise changes

Potential Benefits & Side Effects Research suggests possible recovery, body-composition and sleep effects, but human evidence for this blend is limited and individual results vary

Although raised homocysteine levels might be partly due to a poor vitamin B 12 status, the latter was not related to risk of dementia or Alzheimer's disease in this study (73)

For help managing injection-related [side effects](/guides/retatrutide-side-effects-management-guide), see our companion guide

difficulty breathing

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