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Epidemiologic studies that adjusted for injury severity in their analyses of outcomes from acute alcohol exposure may have obscured the association of mortality and other outcomes with BAC by over adjustment

Treatment ranges from dietary changes and medications like antacids or proton pump inhibitors to surgical repair (typically laparoscopic fundoplication) for severe or paraesophageal cases

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Bifidobacterium breve CCFM1025 attenuates major depression disorder via regulating gut microbiome and tryptophan metabolism: a randomized clinical trial