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Carmel, 2008)

Statements Author contributions T-BC: Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Writing original draft

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Copper-catalyzed azide-alkyne cycloaddition (CuAAC), strain-promoted azide-alkyne cycloaddition (SPAAC) and nitrile oxide-alkyne cycloaddition (NOAC) are the most widely used approaches in biomedical scenarios (Figure 4)

These studies indicate that liver-derived circulating IGF-1 certainly plays a significant role in growth of animals, although it cannot explain all of IGF-1s growth promoting function in the body