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doi: 10.1016/j.immuni.2022.11.009 Summary Keywords mitochondria, mitochondrial dysfunction, rheumatoid arthritis, breakthrough point, synthesis Citation Li S, Huo C, Liu A and Zhu Y (2024) Mitochondria: a breakthrough in combating rheumatoid arthritis

Using mice, human serum, and in vitro experiments, we analyzed the effect of short-term larazotide, a zonulin antagonist, treatment during preclinical phases of arthritis to show the existence of the gutjoint axis and open therapeutic opportunities to prevent arthritis

Int J Mol Sci 21 (7)

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This process is closely associated with autophagy, particularly with NCOA4-mediated ferritinophagy