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This may suggest some involvement of PPAR-mediated signaling, though other PPAR-independent effects of 13-HODE also likely play a role 41,42

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doi: 10.1016/j.phymed.2022.154615 Summary Keywords Scrophulariae Radix , endocrine disorders, thyroid diseases, diabetes mellitus, pharmacological effects, mechanisms Citation Song J, Li J, Shi H, Liu H, Qu Y and Wang F (2025) The mechanism and application of Scrophulariae Radix in the treatment of endocrine disorders: focusing on thyroid diseases and diabetes mellitus

doi: 10.7860/JCDR/2014/10258.5292 4 BarcelouxD