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And I know this reads like geek speak and may have you feeling like you ARE back in senior year chem class, so let me explain it with an Iron Man analogy

Transferrin receptor is a specific ferroptosis marker

However, natural glutathione levels decline with age, environmental toxins, stress, alcohol, and poor diet

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GST pulldowns, which we discussed above, are probably the most common form of this type of experiment, but you can perform analogous isolation experiments with other protein tags including his-tags, flag-tags, and strep-tags (Figure 8)