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doi: 10.1210/jcem.86.3.7312 [DOI] [PubMed] [Google Scholar] 69

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Despite proven efficacy, both treatments are limited by inconsistent responses, the need for ongoing use, recurrence after discontinuation, and side effects such as scalp irritation and sexual or hormonal issues [6, 7]

In another study, the response to combination therapy of zinc and IFN- in HBV infection was not significantly different than IFN- alone

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PMID 23810174