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To investigate the role of proteasome-, lysosome-, or autophagosome-dependent pathways in the reduction of TGFBR1 protein induced by SIRT2, the inhibitory effects were evaluated using proteasome inhibitor MG132, lysosome inhibitor NH 4 Cl, and autophagosome inhibitor 3-MA

Studies have consistently shown creatine supplements have resulted in increased lean muscle mass and exercise ability when used with short-duration, high-intensity exercise

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Its biological functions include: (1) adjusting gene performance (May et al., 1998

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