It has a strong background in skin repair research, and early hair-related studies suggest it may support the hair follicle environment, dermal papilla cell activity, and healthier-looking hair
Nat Rev Nephrol 12:402413 Shahzad MH, Feng L, Su X, Brassard A, Dhoparee-Doomah I, Ferri LE, Spicer JD, Cools-Lartigue JJ (2022) Neutrophil extracellular traps in Cancer therapy resistance
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However, since NO is freely diffusible across membranes, it is possible that the mitochondrial production of peroxynitrite may derive from extramitochondrial NO diffusing into mitochondria to react with superoxide generated by ETC
The answer depends partly on reaching an effective dose, but rushing to get there creates more problems than it solves